The UK's National Chlamydia Screening Programme (NCSP) is an opportunistic screening programme for chlamydia in under-25s that has been rolled out in England since 2003. All anonymised data from the NCSP from April 2006 to March 2007 were analysed in the South East region. Only 1% of men under 25 and 3% of women in this age group in the South East underwent chlamydia screening in the fourth year of the national programme. Community contraception services, youth services and general practice detected the majority of positive results in both sexes, nearly half of positive men and almost two-thirds of positive women. 'The authors suggest that a strategy that can give access to both high numbers of the target population and a wide variety of individuals needs to be developed. They call for greater engagement with general practice, contraceptive services and youth clinics - all of which can generate large volumes with relatively high positivity compared with other settings. '