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Bland P. Predicting which older patients will fail to respond to antidepressants. Practitioner 2015; 259 (1785): 8

Predicting which older patients will fail to respond to antidepressants

24 Sep 2015Registered users

Older people with higher levels of depression severity are unlikely to respond to first-line antidepressant treatment, particularly if they have chronic depression, guilt or marked functional impairment, a US open label study has found. A total of 453 participants were recruited in a secondary care setting and completed the study. Eligible patients were aged 60 or above with current non-psychotic unipolar major depression.

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